Dexatobrin ophthalmic suspension 5 ml

Tradename

Dexatobrine

Dexatobrin

Compound:

Each 1 ml of the drug contains:

Tobramycin 0.3%

Dexamethasone 0.1%

Auxiliary components:

benzalkonium chloride, disodium edetate, sodium chloride, anhydrous sodium sulfate, tyloxapol, hydroxyethylcellulose, sodium hydroxide or sulfuric acid (to maintain pH), purified water.

Properties

Combined drug with antibacterial and anti-inflammatory action for topical use in ophthalmology.

Tobramycin is a broad-spectrum antibiotic from the aminoglycoside group. Active against gram-positive and gram-negative microorganisms: Staphylococcus spp. (including Staphylococcus aureus, Staphylococcus epidermidis /including strains resistant to penicillin/), Streptococcus spp. (including some β-hemolytic species of group A, some non-hemolytic species and some strains of Streptococcus pneumoniae), Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, Proteus vulgaris, Haemophilus influenzae, Haemophilus aegyptius , Moraxella lacunata, Acinetobacter calcoaceticus, as well as some strains of Neisseria spp.

Dexamethasone is a glucocorticosteroid. It has a pronounced anti-inflammatory, anti-allergic and desensitizing effect. Has an anti-exudative effect.

Indications

— prevention of postoperative infectious complications;

-blepharitis;

-conjunctivitis;

Dosage and administration

Eye drops are instilled 1-2 drops into the conjunctival sac of the affected eye (or eyes) every 4-6 hours. In the first 24-48 hours, the dose can be increased to 1-2 drops into the conjunctival sac every 2 hours.

Contraindications

— viral diseases of the cornea and conjunctiva (including keratitis caused by Herpes simplex, chickenpox);

— mycobacterial eye infection;

— fungal diseases of the eyes;

Side effects

Allergic reactions: itching and swelling of the eyelids, redness of the conjunctiva.

On the part of the organ of vision (due to dexamethasone): increased intraocular pressure, formation of posterior subcapsular cataracts, slowing down the wound healing process.

Others: the development of a secondary infection (including bacterial), as a result of suppression of the patient’s protective reaction. The appearance of non-healing ulcers on the cornea after long-term treatment with corticosteroids may indicate the development of a fungal infection.