Amosar 50 mg 30 tablets

Tradename

Amosar

Amosar

Composition

Each p/ o tablet contains:

Losartan — 50mg.

Auxiliary components: lactose, calcium phosphate, microcrystalline cellulose, colloidal silicon dioxide, Povidone, sodium stearyl fumarate, quinoline yellow, polyethylene glycol, titanium dioxide, cellulose.

Properties

Losartan is an antihypertensive agent. It is a non-peptide angiotensin Il receptor blocker. By blocking receptors of the ATI type (with the participation of which the main effects of angiotensin Il are realized), losartan prevents and eliminates the vasoconstrictor effect of angiotensin Il, its stimulating effect on the secretion of aldosterone by the adrenal gla and some other effects of angiotensin ll. It is characterized by a long-term effect (24 hours

or more).

Indications

arterial hypertension (a decrease in the combined incidence of stroke and myocardial infarction). Kidney protection in patients with type 2 diabetes mellitus with proteinuria slowing the progression of renal failure, the incidence of end-stage chronic renal failure, mortality rates, and a decrease in proteinuria. Chronic heart failure (as part of combination therapy, with intolerance or ineffectiveness of therapy with ACE inhibitors).

Mode of application:

the average oral dose is 50 mg 1 time / day. If necessary, the dose can be reduced to 25 mg / day or increased to 100 mg / day, in the latter case, it can be used 2 times / day.

Contraindications

Pregnancy, lactation, childhood and adolescence up to 18 years, hypersensitivity to losartan.

Precautions:

should be used with caution in case of arterial hypotension, bilateral renal artery stenosis or stenosis of an artery of a single kidney, with renal / hepatic insufficiency. In patients receiving high-dose diuretic therapy at the beginning of losartan treatment, symptomatic arterial hypotension may occur. In case of impaired renal function, the dose of losartan should be reduced. In patients with liver disease, losartan should be used in low doses. With cirrhosis of the liver, the concentration of losartan in the blood plasma increases significantly. During the period of treatment, the level of potassium in the blood should be regularly monitored, especially in elderly patients with impaired renal function. The simultaneous use of losartan with potassiumsparing diuretics should be avoided.

Side effects

headache, dizziness, orthostatic hypotension, hyperkalemia, angioedema (including swelling of the face, lips, pharynx and / or tongue), urticaria, itching, diarrhea, increased ALT activity, impaired renal function, myalgia.

Storage

Keep out of the reach of children.

Packaging:

The package contains 1 or 3 blisters of 10