Atacand plus 32/25 mg 14 tablets

Tradename

Atacand plus

Atacand plus

Structure:

Each tablet contains:

32 mg condesartan and 25 mg hydrochlorothiazide

Auxiliary components:

Carmelose calcium, hydroxyprocelulose, iron oxide red, iron oxide yellow, lactose monohydrate, magnesium stearate, starch, macrogol.

Properties

Angiotensin II is the primary vasoactive hormone of the renin-angiotensin-aldosterone system; it plays a role in the pathophysiology of arterial hypertension (AH), heart failure, and other cardiovascular disorders. The main physiological effects of angiotensin II, such as vasoconstriction, stimulation of aldosterone secretion, regulation of salt and water homeostasis, and stimulation of cell growth, are mediated by the type 1 receptor

Hydrochlorothiazide blocks sodium reabsorption, mainly in the distal renal tubules, and promotes the excretion of sodium, chloride and water. Renal excretion of potassium and magnesium increases depending on the dose of the drug, while calcium is reabsorbed to a greater extent. Hydrochlorothiazide reduces plasma and extracellular fluid volume and decreases cardiac output and blood pressure. With prolonged therapy, reduced peripheral resistance contributes to a decrease in blood pressure.

Candesartan and hydrochlorothiazide have an additive antihypertensive effect.

Indications

Essential hypertension in cases where candesartan monotherapy with cilexetil or hydrochlorothiazide is insufficient.

Method of administration and dosage:

Take once daily before or after meals.

Contraindications

— hypersensitivity to candesartan cilexetil or other components of the drug;

— severe hepatic impairment and / or cholestasis;

— pregnancy, breastfeeding;

Side effects

From the nervous system: dizziness / vertigo, headache.

Infections and infestations: respiratory tract infections.

Vascular disorders: arterial hypotension.

Storage

In a cool dry place at a temperature not exceeding 30 degrees

Packaging:

The cardboard box contains 14 tablets and paper instructions.