Flixonase nasal spray 50 mcg / dose 120 doses

Tradename

Flixonase

Flixonase

Composition and form of release:

Dosed nasal spray in the form of an opaque suspension of white color, free from foreign particles. The bottle contains 120 doses.

Each dose contains 50 mcg of micronized fluticasone propionate.

Pharmachologic effect:

Intranasal glucocorticosteroid. It has a pronounced anti-inflammatory effect. With intranasal administration, there is no systemic effect, practically does not inhibit the hypothalamic-pituitary-adrenal system.

The anti-inflammatory effect of fluticasone propionate is realized as a result of its interaction with glucocorticoid receptors. Fluticasone propionate reduces the production of inflammatory mediators and a number of biologically active substances (including histamine, prostaglandins, leukotrienes, cytokines) during the early and late phases of an allergic reaction. It has a fast anti-

inflammatory effect on the nasal mucosa. Antiallergic effect appears within 2-4 hours after the first application. Reduces sneezing, itchy nose, rhinorrhea, nasal congestion, sinus discomfort, and pressure around the nose and eyes. It also relieves eye symptoms associated with allergic rhinitis.

Fluticasone propionate improves the quality of life of patients, including physical and social activity.

Indications

Treatments for perennial and seasonal allergic rhinitis, including hay fever:

pain, feeling of pressure in the area of the paranasal sinuses;

nasal congestion, sneezing, itching in the nose;

Contraindications

Hypersensitivity to fluticasone propionate

and other components of the drug;

Children under 4 years old;

Side effects

Determination of the frequency of side effects: very often (? 1/10), often (? 1/100 and < 1/10), infrequently (? 1/1000 and <1/100), rarely (? 1/10 000 and / 1000), very rare (<1/10 000, including isolated cases).

From the immune system: very rarely hypersensitivity reactions, incl. bronchospasm,

rash, swelling of the face and tongue, anaphylactic reactions, anaphylactoid reactions.