Flucoral 150 mg 2 capsules

Tradename

Flucoral

Flucoral

Structure:

Each hard gelatin capsule contains:

Fluconazole 150mg

Auxiliary components:

lactose monohydrate, corn starch, colloidal silicon dioxide, magnesium stearate, sodium lauryl sulfate.

Properties

Fluconazole is an antifungal triazole. It is a potent and selective inhibitor of fungal enzymes required for the synthesis of ergosterol. Active against opportunistic mycoses such as infections caused by Candida spp. including systemic candidiasis in animals with weakened immunity; with Cryptococcus neoformans, including intracranial infections, with Microsporum spp. and with Trichophyton spp. Fluconazole is very specific for fungal cytochrome P450-dependent enzymes. It has been shown that fluconazole does not affect plasma testosterone concentration in men or steroid concentration in women of childbearing age when taken 50 mg daily for up to 28 days. No clinically significant effect was observed on endogenous steroid levels or on ACTH stimulated response in healthy male volunteers. taking fluconazole 200-400 mg day. Interaction studies with antipyrine sho that a single or multiple dose of fluconazole 50 mg does not affect metabolism.

Indications

Treatment of acute or recurrent candidal vaginitis, as well as for the treatment of partners with associated candidal balanitis.

Mode of application:

Adults (16-60 years old): 1 capsule should be swallowed whole. Not recommended for patients over 60 years of age. In patients with renal impairment, there is no separate dosing regimen for a single therapy.

Contraindications

Children under 16 years of age, hypersensitivity to fluconazole, related azole compounds or any of the excipients in the composition. Fluconazole should not be taken with terfenadine, cisapride or ergot derivatives. Pregnancy, breastfeeding.

Precautions:

Do not use the drug without first consulting your doctor. If you have had thrush more than 2 times in the past 6 months, liver disease, kidney disease, or patients with jaundice. If suffer from any other chronic medical condition. If you or your partner have been

Side effects

Most common: headache, abdominal pain, diarrhea, nausea, vomiting, elevated alkaline

phosphatase levels, and rash. Diseases of the blood and lymphatic system: anemia. Rarely: agranulocytosis, leukopenia, thrombocytopenia, neutropenia. Immune system disorders: rare anaphylaxis. Metabolism and nutritional disorders: infrequently: decreased appetite. Rarely:

hypercholesterolemia, hypertriglyceridemia, hypokalemia. Mental disorders: drowsiness, insomnia. Nervous system disorders: infrequently: convulsions, paresthesia, dizziness, taste perversion. Rare: tremor. Gastrointestinal disorders: infrequently:

Storage

Store at a temperature not exceeding 30C in a dry place out of the reach of children.

Packaging:

Cardboard box, consists of a blister with 2 capsules and paper instructions.