
Dexafen syrup 120 ml
Trade name:
Dexaphen
Dexaphen
Composition
Each 5 ml of syrup contains:
Dexamethasone 0.5 mg
Chlorpheniramine maleate 2 mg.
Auxiliary components:
Propylene glycol, methylparaben, propylparaben, sorbitol, sucrose, diode edetate, sodium metabisulfite, citric acid anhydros, sodium citrate anhydrous, carmoisine, strawberry flavor, purified water.
Properties
Dexamethasone is a synthetic glucocorticoid (GCS), a methylated derivative of fluoroprednisolone. It has anti-inflammatory, anti-allergic, immunosuppressive effects, increases the sensitivity of beta-adrenergic receptors to endogenous catecholamines.
A feature of the action is a significant inhibition of the function of the pituitary gland and an almost complete absence of mineralocorticosteroid activity.
Chlorpheniramine maleate is a blocker of histamine HI-receptors, has antiserotonin, antihistamine, weak anticholinergic, sedative effect. Reduces the severity of allergic reactions mediated by the action of histamine, reduces capillary permeability, narrows blood vessels, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses; reduces local exudative manifestations, suppresses the symptoms of allergic rhinitis: sneezing, rhinorrhea, itchy eyes, nose.
Indications
Dexafen is used for inflammatory conditions and allergic diseases such as:
Allergic rhinitis;
Otitis media;
Contraindications
Hypersensitivity to components;
Children under 2 years old;
Bronchial asthma ;
Side effects
May cause mild sedation;
Allergic reactions.
From the nervous system: delirium, disorientation, euphoria, hallucinations, manicdepressive psychosis, depression, paranoia, increased intracranial pressure, nervousness or anxiety, insomnia, dizziness, vertigo, cerebellar pseudotumor, headache, convulsions.