Buspar 15 mg 10 tablets

Tradename

Buspar

Buspar

Composition

Each tablet contains:

15 mg buspirone hydrochloride

Auxiliary components:

lactose monohydrate, microcrystalline cellulose, sodium carboxymethyl starch, magnesium stearate, colloidal anhydrous silicon dioxide.

Properties

Anxiolytic drug (tranquilizer) of the nonbenzodiazepine series also has an antidepressant effect. Unlike classical anxiolytics, it does not possess antiepileptic, sedative, hypnotic and muscle relaxant effects.

The mechanism of action is associated with the effect of buspirone on the serotonergic and dopaminergic systems. Selectively blocks presynaptic dopamine receptors and increases the rate of excitation of dopamine neurons in the midbrain. In addition, buspirone is a selective partial agonist of 5-HTIA serotonin receptors. Buspirone has no significant effect on benzodiazepine receptors and does not affect the binding of GABA, does not have negative effect on psychomotor functions,

and withdrawal syndrome. Does not potentiate the effects of alcohol. In terms of anxiolytic activity, buspirone is approximately equal to benzodiazepines.

Indications

generalized anxiety disorder (GAD);

adjuvant therapy for depressive disorders (the drug is not prescribed for depression monotherapy).

Method of administration and dosage:

Contraindications

-increased sensitivity to drug components;

— severe renal failure (GFR < 10 ml / min);

-severe hepatic impairment (prothrombin time> 18 sec);

Contraindications

-increased sensitivity to drug components;

— severe renal failure (GFR < 10 ml / min);

-severe hepatic impairment (prothrombin time> 18 sec);

Side effects

From the side of the cardiovascular system: often — chest pain;

From the nervous system: often — dizziness, headache, increased nervous excitability, sleep disturbances.

From the senses: often — tinnitus.