Buspar 10 mg 20 tablets

Tradename

Buspar

Buspar

Structure:

Each tablet contains:

10mg buspirone hydrochloride

Auxiliary components:

lactose monohydrate, microcrystalline cellulose, sodium carboxymethyl starch, magnesium stearate, colloidal anhydrous silicon dioxide.

Properties

Anxiolytic drug (tranquilizer) of the non-benzodiazepine series also has an antidepressant effect. Unlike classical anxiolytics, it does not have antiepileptic, sedative, hypnotic and muscle relaxant effects.

The mechanism of action is associated with the effect of buspirone on the serotonergic and dopaminergic systems. Selectively blocks presynaptic dopamine receptors and increases the rate of excitation of dopamine neurons in the midbrain. In addition, buspirone is a selective partial agonist of 5-HT1A serotonin receptors. Buspirone has no significant effect on benzodiazepine receptors and does not affect the binding of GABA, does not have a negative effect on psychomotor functions, does not cause tolerance, drug dependence and withdrawal syndrome. Does not potentiate the effects of alcohol. In terms of anxiolytic activity, buspirone is approximately equal to benzodiazepines.

Indications

generalized anxiety disorder (GAD);

adjuvant therapy for depressive disorders (the drug is not prescribed for depression monotherapy).

Method of administration and dosage:

Contraindications

-increased sensitivity to the components of the drug;

— severe renal failure (GFR <10 ml / min);

— severe hepatic impairment (prothrombin time> 18 sec);

Side effects

From the side of the cardiovascular system: often — chest pain;

From the nervous system: often — dizziness, headache, increased nervous irritability, sleep disturbances.

From the senses: often — tinnitus.