Augmentin 457 mg / 5 ml powder for suspension preparation 70 ml

Trade name:

Augmentin

Augmentin

Composition

Each 5 ml of the finished suspension contains 400 mg of amoxicillin and 57 mg of clavulanic acid.

Auxiliary components:

xanthan gum — 12.5 mg, aspartame — 12.5 mg, succinic acid — 0.84 mg, colloidal silicon dioxide — 25 mg, hypromellose — 79.65 mg, strawberry flavor 1 — 15 mg, silicon dioxide — up to 900 mg.

Properties

Amoxicillin is a semi-synthetic penicillin (betalactam antibiotic) that inhibits one or more enzymes (known as penicillin-binding proteins) in the biosynthesis of bacterial peptidoglyc which is the unifying structural component the bacterial cell wall. Inhibition of peptidoglycan synthesis leads to a thinning of the cell wall, which subsequently leads to lysis and cell death. Amoxicillin is destroyed by the action of lactamases produced by resistant bacteria, and therefore the spectrum of activity of amoxicillin itself does not include microorganisms that produce these enzymes.

Clavulanic acid is a lactamase inhibitor structurally related to penicillins. Clavulanic acid blocks the action of certain lactamase enzymes, thereby preventing the inactivation of amoxicillin. Clavulanic acid alone does not show a clinically significant antibacterial effect.

Indications

Augmentin is indicated for the treatment of the following infections in adults and children:

Acute bacterial sinusitis

Acute otitis media

Contraindications

-Hypersensitivity to amoxicillin, clavulanic acid, other components of the drug, beta-lactam antibiotics (for example, penicillins, cephalosporins) in history;

previous episodes of jaundice or abnormal liver function when using a combination of amoxicillin with clavulanic acid in history;

children up to 2 months of age (for powder for preparation of suspension for oral administration 400 mg / 57 mg in 5 ml);

Side effects

Infectious and parasitic diseases: often candidiasis of the skin and mucous membranes.

From the digestive tract:

adults: very often — diarrhea; often — nausea, vomiting;