Alzmenda 20 mg 21 tablets

Tradename

Alzmenda

Alzmenda

Compound:

Each tablet contains:

Memantine hydrochloride 20 mg

Auxiliary components:

Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, macrogol, titanium dioxide.

Properties

A remedy for dementia. It is a non-competitive antagonist of glutamate NMDA receptors (including in the substantia nigra), as a result of which it reduces the excessive stimulating effect of cortical glutamate neurons on the neostriatum, which develops against the background of insufficient release of dopamine. By reducing the supply of Ca2 + to neurons, the possibility of their destruction decreases.

It has a nootropic, cerebrovasodilating, antihypoxic and psychostimulating effect.

Improves impaired memory, increases the ability to concentrate, reduces fatigue and symptoms of depression, and reduces skeletal

Indications

Moderate to severe dementia in Alzheimer’s disease

Method of administration and dosage:

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Contraindications

failure; pregnancy; lactation period

(breastfeeding); children and adolescents up to 18 years of age (the effectiveness and safety of the drug have not been established).

With care: epilepsy, thyrotoxicosis, a predisposition to the development of seizures, the simultaneous use of NMDA receptor antagonists (amantadine, ketamine, dextromethorphan), factors that increase the pH of urine (a sharp change in diet, for example, switching to vegetarianism, abundant intake of alkaline gastric buffers), renal tubular acidosis, severe urinary tract infections caused by Proteusspp., myocardial infarction (in history), heart failure, uncontrolled arterial hypertension, renal failure, mild to moderate hepatic impairment (Child-Pugh class A and B).

Side effects

From the immune system: often hypersensitivity reactions.

From the side of the psyche: often drowsiness; infrequently — confusion, hallucinations (mainly observed in patients with Alzheimer’s disease at the stage of severe dementia), the frequency is unknown — mental reactions.

From the nervous system: often — dizziness, imbalance; infrequently — gait disturbance; very rarely — convulsions.