Irbedrin-Dew 300 / 12.5mg 10 tablets

Tradename

Irbedrin-Dew

Irbedrin-Diu

Composition

Each tablet contains:

Irbesartan — 300mg.

Hydrochlorothiazide 12.5mg

Auxiliary components: lactose, crospovidone starch, polysorbate, croscarmellose sodium, red and yellow iron oxide, magnesium stearate.

Properties

Irbedrin-Dew is a combination of two active substances, irbesartan and hydrochlorothiazide. Irbesartan belongs to the group of angiotensin Il receptor antagonists. Angiotensin Il is a substance produced in the body that binds to receptors in blood vessels, causing them to contract, which leads to high blood pressure. Irbesartan prevents the binding of angiotensin-ll to these receptors, causing relaxation of blood vessels and lowering blood pressure. Hydrochlorothiazide is a thiazide diuretic that causes increased urine production and decreased blood pressure.

Indications

treatment of arterial hypertension, when monotherapy with irbesartan or hydrochlorothiazide does not provide adequate control of blood pressure.

Mode of application:

inside, one tablet once a day (the maximum daily dose is -300 / 12.5 mg), regardless of the meal. If it is not possible to achieve target blood pressure values when using the drug, then other antihypertensive drugs can be added to therapy. In renal and hepatic (mild to moderate) insufficiency, dose adjustment is not required.

Contraindications

children up to age 18; hypersensitivity to irbesartan or to any of the other ingredients of the drug; pregnancy and lactation; severe liver or kidney problems, difficulty urinating; with the constant presence of high levels of calcium in the blood or low levels of potassium; diabetes; concomitant use with aliskiren (another medicine to treat high blood pressure).

Precautions:

When using the drug in patients with renal insufficiency, periodic monitoring of the

Side effects

dizziness, headache; tachycardia, excessive decrease in blood pressure, edema of the lower extremities; nausea, vomiting; diarrhea, dryness of the oral mucosa, abdominal pain; changes in the frequency of urination, myalgia, bone pain, weakness in the limbs; skin rash, itching; increased fatigue; weakness.

Storage

Store at a temperature not exceeding 30C in a dry place out of the reach of children.

Packaging:

a cardboard box contains 1 blister of 10 tablets, paper instructions.