Adolor 10 mg 20 tablets

Tradename

Adolor

Adolor

Composition

Each tablet contains:

Ketorolac tromethamine 10 mg

Auxiliary components:

microcrystalline cellulose, magnesium stearate, talc, crospovidone (kollidon CC), lactose monohydrate (milk sugar).

Properties

Ketorolac has a pronounced analgesic effect, also has anti-inflammatory and moderate antipyretic effects.

The mechanism of action is associated with non-selective inhibition of the activity of the enzyme cyclooxygenase 1 and 2, mainly. in peripheral tissues, which results in inhibition of the biosynthesis of prostaglandins modulators of pain sensitivity, thermoregulation and inflammation. Ketorolac is a racemic mixture of [-] S and [+] R enantiomers, with the analgesic effect due to the [-] S form.

The drug does not affect opioid receptors, does not depress respiration, does not cause drug dependence, does not have sedative and anxiolytic effects.

Indications

— pain syndrome of moderate and severe intensity of various origins (including in the postoperative period, with cancer, etc.).

Method of administration and dosage:

Adolor is used orally once or repeatedly, depending on the severity of the pain syndrome. A single dose — 10 mg, with repeated administration, it is recommended to take 10 mg up to 4 times / day, depending the severity of the pain; the maximum daily dose should not exceed 40 mg.

Contraindications

hypersensitivity to ketorolac or other NSAlDs,

«aspirin» asthma, bronchospasm, angioedema;

hypovolemia (regardless of the cause that caused it), dehydration;

Side effects

From the digestive system: often (especially in elderly patients over 65 years of age with a history of erosive and ulcerative lesions of the gastrointestinal tract) — gastralgia, diarrhea; less often — stomatitis, flatulence, constipation, vomiting, a feeling of fullness in the stomach; rarely — nausea, erosive and ulcerative lesions of the gastrointestinal tract (including with perforation and / or bleeding — abdominal pain, spasm or burning sensation in the epigastric region, melena, vomiting like «coffee grounds», nausea, heartburn, etc.), cholestaticjaundic hepatitis, hepatomegaly, acute pancreatitis.

From the urinary system: rarely — acute renal failure, back pain with or without hematuria and / or azotemia, hemolytic uremic syndrome (hemolytic anemia, renal failure, thrombocytopenia, purpura), frequent urination, increased or decreased urine volume, nephritis, edema renal genesis.

From the senses: rarely — hearing loss, ringing in the ears, visual impairment (including blurred vision).