
Augmentin EC 600 powder for suspension preparation 75 ml
Tradename
Augmentin ES
Composition
Each 5 ml of the finished suspension contains:
Amoxicillin 652.78 mg
Clavulanic acid 50.41 mg
Auxiliary components:
colloidal silicon dioxide, succinic acid, hypromellose, xanthan gum, strawberry flavor, aspartame, silicon dioxide.
Properties
Combined preparation of amoxicillin and clavulanic acid — a beta-lactamase inhibitor. Acts bactericidal, inhibits the synthesis of t bacterial wall.
Active against aerobic gram-positive bacteria (including strains producing beta-lactamase):
Staphylococcus aureus; aerobic gram-negative bacteria: Enterobacter spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp.,
Indications
Treatment of infectious and inflammatory diseases caused by sensitive pathogens: lower respiratory tract infections (bronchitis, pneumonia, pleural empyema, lung abscess); ENT infections (sinusitis, tonsillitis, otitis media); infections of the genitourinary system and pelvic organs (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, cervicitis, salpingitis, salpingo-oophoritis, tubo-ovarian abscess, endometritis, bacterial vaginitis, septic abortion, postpartum sepsis, pelvioperitonitis, soft chancre); infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses, abscess, phlegmon, wound infection); osteomyelitis; postoperative infections. Prevention of infections in surgery.
Method of administration and dosage:
Children under 12 years old — in the form of a suspension, syrup or drops for oral administration. A single dose is set dependi on age:
Contraindications
Hypersensitivity to drug components
(including cephalosporins and other beta-
lactam antibiotics); infectious mononucleosis (including when a measles-like rash appears); phenylketonuria; episodes of jaundice or abnormal liver function as a result of amoxicillin / clavulanic acid use in history; CC less than 30 ml / min (for tablets 875 mg / 125 mg).
Side effects
From the digestive system: nausea, vomiting, diarrhea, gastritis, stomatitis, glossitis, increased activity of hepatic transaminases, in isolated cases — cholestatic jaundice, hepatitis, liver failure (more often in the elderly, men, with prolonged therapy), pseudomembranous and hemorrhagic colitis ( can also develop after therapy), enterocolitis, black «hairy» tongue, darkening of tooth enamel.
From the side of hematopoietic organs: a reversible increase in prothrombin time and bleeding time, thrombocytopenia, thrombocytosis, eosinophilia, leukopenia, agranulocytosis, hemolytic anemia.
From the nervous system: dizziness, headache, hyperactivity, anxiety, change in behavior, seizures.