Baclofen 10 mg 20 tablets

Tradename

Baclofen

Composition

Each tablet contains:

Baclofen 10 mg

Auxiliary components:

lactose, potato starch, gelatin, talc, magnesium stearate, ethyl cellulose.

Properties

Muscle relaxant of central action; GABAB receptor agonist. Reducing the excitability of the terminal sections of afferent sensory fibers and suppressing intermediate neurons, it inhibits mono- and polysynaptic transmission of nerve impulses; reduces the pre-tension of muscle spindles. Does not affect the transmission of impulses in the neuromuscular synapses. In neurological diseases, accompanied by skeletal muscle spasticity, relieves painful spasms and clonic seizures. Increases the range of motion in the joints, facilitates passive and active kinesitherapy (exercise, massage, manual therapy).

Indications

Increased muscle tone: — with multiple sclerosis; -in diseases of the spinal cord of infectious, degenerative and traumatic genesis (for example, tumors, syringomyelia, motor neuron diseases, trauma); — with a stroke; with infantile cerebral palsy; — with meningitis; — with traumatic brain injury; — with alcoholism (affective disorders).

Method of administration and dosage:

For adults, the drug is prescribed in an initial dose of 5 mg 3 times / day; gradually increase the dose every 3 days until the optimal therapeutic effect develops (usually up to 3075 mg / day). For patients who require the use of the drug in higher doses (usually up to 3075 mg / day), Baclofen is prescribed in tablets of 25 mg. The maximum daily dose is 100 mg (assigned for a short time in a hospital setting). The duration of the course of therapy depends on the clinical condition of the patient. You should not suddenly stop using Baclofen due to the possible appearance of hallucinations and exacerbation of spastic conditions. The drug is withdrawn gradually (within 1-2 weeks).

Contraindications

peptic ulcer of the stomach and duodenum;

-psychoses;

-Parkinson’s disease;

Side effects

From the side of the central nervous system and the peripheral nervous system: drowsiness, dizziness, gait disturbance, increased fatigue, confusion, apathy, euphoria, depression, paresthesia, ataxia, tremor, nystagmus, paresis of accommodation, hallucinations, convulsions, lowering of the convulsive threshold.

From the digestive system: nausea, vomiting, dry mouth, constipation, diarrhea.

From the urinary system: urinary retention, dysuria, enuresis;