Closol 10 mg / ml spray 50 ml
Tradename
Closol
Composition
Each ml of solution contains:
Clotrimazole 10 mg
Auxiliary components:
Benzalkonium chloride, propylene glycol, cetosteryl alcohol, isopropyl alcohol.
Properties
Broad-spectrum antifungal agent for external use. The action of clotrimazole is associated with a violation of the synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the permeability of the cytoplasmic membrane and causes subsequent cell lysis. In small concentrations it acts fungistatically, in large concentrations it is fungicidal, and not only on proliferating cells. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.
Clotrimazole exhibits fungicidal and fungist activity against dermatomycetes (Trichoph rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum
canis), yeast-like and mold fungi (Candida spp., Including Candida spp., Including Candida Rusta albicans; Torulopsis albicans; Active against the causative agent of varicoloured lichen — Pityrosporum orbiculare
Indications
Fungal infections of the skin; interdigital fungal erosion; mycoses complicated by secondary infection; versicolor versicolor; erythrasma.
Method of administration and dosage:
It is applied externally to the affected skin 2 times a day, morning and evening. The course of treatment is up to 4 weeks.
Contraindications
Hypersensitivity to clotrimazole; I trimester of pregnancy.
Precautions:
If allergic reactions or irritation appear at the site of application of the product, treatment is stopped.
Side effects
From the immune system: allergic reactions, incl. urticaria, shortness of breath, arterial hypotension, fainting.
Skin and subcutaneous tissue disorders: rash,itching, blisters, peeling, pain / discomfort, swelling, burning, irritation, erythema, tingling.
Storage method: