Coloverin 135 mg 30 tablets

Tradename

Coloverin

Composition

Each tablet contains:

Mebeverine hydrochloride 135 mg

Properties

Myotropic antispasmodic, has a direct effect on the smooth muscles of the gastrointestinal tract without affecting the normal intestinal motility. The exact mechanism of action is unknown, but multiple mechanisms, such as decreased ion channel permeability, blockade of norepinephrine reuptake, local anesthetic action, and altered water absorption can cause mebeverine to act locally on the gastrointestinal tract. Through these mechanisms, mebeverine exhibits an antispasmodic effect, normalizing intestinal motility and not causing constant relaxation of smooth muscle cells of the gastrointestinal tract («hypotension»).

Indications

Symptomatic treatment of bowel pain, cram s, dysfunction and discomfort associated with irritable bowel syndrome (symptoms may include abdominal pain, cramping, bloating and

flatulence, changes in stool frequency

(diarrhea, constipation or alternating diarrhea and constipation), changes in constipation chair).

Side effects

Skin and subcutaneous tissue disorders: urticaria (allergic rash), angioedema (serious allergic reaction, which may include: difficulty breathing, swelling of the face, neck, lips, tongue, throat), facial edema, exanthema (skin rash).

From the immune system: hypersensitivity reactions (anaphylactic reactions — serious allergic reactions that may include difficulty breathing, rapid pulse, a sharp decrease in blood pressure (weakness and dizziness), increased sweating).

Storage method: