Биоглита плюс 15/500 мг 20 таблеток
Trade name:
Bioglite plus
Bioglita plus
Composition
Each tablet contains:
Pioglitazone 15 mg
Metformin hydrochloride 500mg
Auxiliary components:
hypromellose (hydroxypropyl methylcellulose), sodium carmellose, povidone, colloidal anhydrous silicon dioxide, calcium hydrogen phosphate, talc, magnesium stearate, hydroxypropyl cellulose, sodium croscarmellose.
Properties
Pioglitazone. Oral hypoglycemic agent. Reduces the insulin resistance of peripheral and liver tissues, which leads to increased insulin-dependent glucose uptake by tissues and decreased hepatic glucose synthesis. Pioglitazone is a potent selective agonist of peroxisome proliferator-activated gamma receptors (PPAR). Activation of nuclear receptors for PPAGR simulates the transcription of a number of insulin-sensitive genes that are involved in glucose control and lipid metabolism.
Metformin. An oral hypoglycemic agent use to treat type Il diabetes. Reduces the concentration of cholesterol and trialvcerl
in blood plasma, increases the concentration of free fatty acids and glycerol.
Indications
— are prescribed for non-insulin dependent diabetes mellitus.
Diabetes mellitus type 2, for adults.
Method of administration and dosage:
Contraindications
hypersensitivity to active substances or any component of the drug. Kidney disease or renal dysfunction, acute myocardial infarction, acute
or chronic metabolic acidosis, diabetic ketoacidosis, lactic acidosis and conditions that increase the risk of its development (shock, infectious diseases, alcoholism, anesthesia, old age, hypovitaminosis B); During pregnancy and breastfeeding; childhood.
Precautions:
Side effects
from the gastrointestinal tract: nausea, diarrhea, pain in the stomach, constipation, vomiting, metallic taste in the mouth. Reactions disappear when the dose is reduced
Dermatological reactions: rash, urticaria, erythema, skin redness.
Others: headache, dizziness, fluid retention and weight gain, risk of fractures, lactic acidosis; hypoglycemia.