Jusprin 81 mg 60 tablets

Tradename

Juspirin

Jusprin

Compound:

Acetylsalicylic acid 81 mg

Auxiliary components:

Cellulose, starch, stearic acid, aerosil, talc, isopropyl alcohol.

Properties

NSAlDs. It has anti-inflammatory, analgesic and antipyretic effects, and also inhibits platelet aggregation. The mechanism of action is associated with inhibition of the activity of COX, the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. A decrease in the content of prostaglandins (mainly El) in the center of thermoregulation leads to a decrease in body temperature due to vasodilation of the skin and an increase in sweating. The analgesic effect is due to both central and peripheral effects. Reduces platelet aggregation, adhesion and thrombus formation by suppressing the synthesis of thromboxane A2 in platelets.

Reduces mortality and the risk of developing myocardial infarction in unstable angina

pectoris. It is effective in the primary prevention of cardiovascular diseases and in the secondary prevention of myocardial infarction. In a daily dose of 6 g or more, it suppresses the synthesis of prothrombin in the liver and increases the prothrombin time.

Indications

Rheumatism, rheumatoid arthritis, infectiousallergic myocarditis; fever with infectious and inflammatory diseases; pain syndrome of weak and moderate intensity of various origins (including neuralgia, myalgia, headache); prevention of thrombosis and embolism; primary and secondary prevention of myocardial infarction; prevention of cerebra circulation disorders by ischemic type.

Method of administration and dosage:

Take orally with meals.

Contraindications

Erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, gastrointestinal bleeding, «aspirin triad», a history of indications of urticaria, rhinitis caused by the intake of acetylsalicylic acid and other NSAlDs, hemophilia, hemorrhagic diathesis, hypoprothrombinemia, dissecting portal aneurysm vitamin K deficiency, hepatic and / or renal failure, glucose-6-phosphate dehydrogenase deficiency, Reye’s syndrome, childhood (up to 15 years — the risk of developing Reye’s syndrome in children with hyperthermia against a background of viral diseases), I and Ill trimesters of pregnancy, lactation , hypersensitivity to acetylsalicylic acid and other salicylates.

Precautions:

It is used with caution in patients with liver and

Side effects

From the digestive system: nausea, vomiting, anorexia, epigastric pain, diarrhea; rarely — the occurrence of erosive and ulcerative lesions, bleeding from the gastrointestinal tract, liver dysfunction.

From the side of the central nervous system: with prolonged use, dizziness, headache, reversible visual impairments, tinnitus, aseptic meningitis are possible.

From the hematopoietic system: rarely thrombocytopenia, anemia.