Diax 200 mg 12 capsules

Tradename

Diax

Composition

Each capsule contains:

Nifuroxazide 200 mg

Auxiliary components:

Talc, magnesium stearate, aerosil, lactose monohydrate, gelatin, titanium dioxide.

Properties

Effective against gram-positive (staphylococci, streptococci) and some gram-negative (Salmonella, Shigella, Klebsiella, Escherichia coli) bacteria, does not affect the composition of the normal microflora of the large intestine. Presumably inhibits the activity of dehydrogenases and protein synthesis in bacterial cells. Does not cause the emergence of drug-resistant strains, as well as crossresistance with other antibacterial drugs. The effectiveness of the action does not depend the pH in the intestinal lumen, on the sensitivity of microorganisms to antibiotics. The drug acts exclusively in the intestinal

lumen, since it is practically not absorbed from the digestive tract.

Indications

Diarrhea (acute and chronic) caused by grampositive (staphylococci and streptococci), as well as some gram-negative (Salmonella, Shigella, Klebsiella, Escherichia coli) bacteria, diarrhea with food intoxication, appendicitis, chronic autoimmune gastritis; diarrhea caused by antibiotic therapy, changes in the natural bacterial flora of the large intestine of various etiologies, diseases accompanied by diarrhea.

Toxic diarrhea caused by gram-negative bacteria (Salmonella, Shigella, Klebsiella,

Escherichia coli)

Contraindications

Hypersensitivity (including to 5-nitrofuran derivatives); in children — prematurity and age less than 2 months.

Precautions:

During the treatment of acute diarrhea, it is necessary to replenish the loss of body fluids (orally or parenterally, depending on the patient’s condition).

Side effects

From the hematopoietic and lymphatic system:

One case of granulocytopenia has been described.

From the gastrointestinal tract: