Lamifen 250 mg 14 tablets

Tradename

Lamifen

Composition

Each tablet contains:

Terbinafine 250 mg

Auxiliary components: hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, silicon dioxide, calcium stearate.

Properties

Antifungal agent, belongs to the group of aplylamines, has a wide spectrum of antifungal action. In low concentrations, it has a fungicidal effect on dermatophytes Trichophyton spp. (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum), Microsporum canis,

Epidermophyton floccosum, molds (eg, Scopulariopsis brevicaulis), yeast albicans, mainly albicans. For Candida spp. and their mycelial forms, depending on the type of fungus, have a fungicidal or fungistatic effe Terbinafine disrupts the early stage of biosynthesis of the main component of the cell membrane of the fungus ergosterol by inhibiting the enzyme squalene epoxidase.

When administered orally, it is not effective in the treatment of varicoloured lichen caused by Pityrosporum ovale, Pityrosporum orbiculare, Malassezia furfur.

Indications

Mycoses of the scalp (trichophytosis, microsporia); fungal diseases of the skin and nails (onychomycosis) caused by Trichophyton spp. (T. rubrum, T. mentagrophytes, T.

verrucosum, T. violaceum), Microsporum spp. (M. canis, M. gypseum) and Epidermophyton floccosum; severe, widespread dermatomycosis of the smooth skin of the trunk and extremities, requiring systemic treatment; candidiasis of the skin and mucous membranes.

Method of administration and dosage:

Contraindications

Acute or chronic liver disease; children under 2 years old; lactation period; hypersensitivity to terbinafine.

Carefully.

Pregnancy; renal failure; alcoholism; oppression of bone marrow hematopoiesis; tumors; metabolic diseases; occlusive vascular disease of the extremities.

Side effects

From the side of the central nervous system: often — headache, dizziness.

From the hematopoietic system: very rarely (<0.01%) — neutropenia, agranulocytosis, thrombocytopenia.

From the immune system: rarely anaphylactoid reactions, including angioedema, exacerbation of systemic lupus erythematosus.