No-Uric 300 mg 20 tablets

Tradename

No-Uric

Composition

Each tablet contains:

Allopurinol 300 mg

Auxiliary components:

lactose monohydrate (milk sugar), microcrystalline cellulose, sodium carboxymethyl starch (primogel), food gelatin, magnesium stearate, colloidal silicon dioxide (aerosil).

Properties

A drug that disrupts the synthesis of uric acid.

It is a structural analogue of hypoxanthine. Inhibits the enzyme xanthine oxidase, which is involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid. This is due to a decrease in the concentration of uric acid and its salts in body fluids and urine, which contributes to the dissolution of existing ur deposits and prevents their formation in tissues and kidneys. When allopurinol is taken, the urinary excretion of hypoxanthine and xanthine increases.

Indications

Treatment and prevention of gout and hyperuricemia of various origins (including in combination with nephrolithiasis, renal failure, urate nephropathy). Recurrent mixed calcium oxalate kidney stones in the presence of hyperuricosuria. Increased formation of urates due to enzyme disorders. Prevention of acute nephropathy with cytostatic and radiation therapy of tumors and leukemias, as well as with complete medical fasting.

Method of administration and dosage:

The optimal dosage regimen is determined by the doctor. The compliance of the used dosage form of a particular drug with indications for use and dosage regimen should be strictly observed.

Contraindications

Severe liver and / or kidney dysfunction, pregnancy, lactation, hypersensitivity to allopurinol.

Precautions:

Allopurinol should be used with caution in case of impaired liver and / or kidney function (in both cases, a dose reduction is required), hypothyroidism. In the initial period of the course of therapy with allopurinol, a systematic assessment of liver function indicators is

Side effects

Allergic reactions: skin rash, hyperemia, itching; in some cases — angioimmunoblastic lymphadenopathy, arthralgia, fever, eosinophilia, fever, Stevens-Johnson syndrome, Lyell’s syndrome.

Dermatological reactions: in isolated cases furunculosis, alopecia, hair discoloration.

On the part of the digestive system: possibl dyspeptic symptoms (including nausea, vomiting), diarrhea, transient increase in the