Clopex 75 mg 30 tablets

Tradename

Clopex

Clopex

Composition

Each tablet contains:

Clopidogrel 75 mg

Auxiliary components:

pregelatinized starch, anhydrous lactose (anhydrous milk sugar), macrogol (polyethylene glycol 6000), magnesium stearate, microcrystalline cellulose, hydrogenated castor oil.

Properties

Specific and active inhibitor of platelet aggregation; has a coronary dilating effect. Selectively reduces the binding of ADP to platelet receptors and the activation of GPII Illa receptors by ADP, weakening platelet aggregation.

Reduces platelet aggregation induced by other agonists, preventing their activation by released ADP, does not affect the activity of phosphodiesterase (PDE). It binds irreversibly to platelet ADP receptors, which remain immune to ADP stimulation throughout the life cycle (about 7 days).

Indications

Prevention of atherothrombotic events in patients with myocardial infarction, ischemic stroke, or diagnosed peripheral arterial occlusive disease.

Prevention of atherothrombotic events (in combination with acetylsalicylic acid) in patients with acute coronary syndrome:

without ST-segment elevation (unstable angina or myocardial infarction without Q wave), including patients who underwent stenting during percutaneous coronary intervention;

Contraindications

severe liver failure;

active bleeding (including bleeding from a peptic ulcer or intracranial hemorrhage);

-pregnancy;

Side effects

From the side of the cardiovascular system: often — hematoma; very rarely — heavy bleeding, bleeding from the surgical wound, vasculitis, lowering blood pressure.

From the respiratory system: very often nosebleeds; very rarely — bronchospasm, interstitial pneumonitis, pulmonary hemorrhage, hemoptysis.

From the digestive system: often gastrointestinal bleeding, diarrhea, abdomi pain, dyspepsia.