
Mixderm cream 15 g
Tradename
Mixderm
Mixderm
Composition
Each gram of cream contains:
Betamethasone 0.5 mg
Gentamicin 0.1 mg
Tolnaftate 10 mg
Clioquinol 10 mg
Auxiliary components:
Chlorocresol, texophor, cetyl alcohol, petrolatum, sodium bisphosphate, mineral oil, sodium hydroxide and purified water.
Properties
Combined preparation for external use.
Mixderm combines the anti-inflammatory, antipruritic, antiallergic and antiexudative effects of betamethasone dipropionate GCS with the antifungal activity of Tolnaftate and the broad antibacterial effect of gentamicin sulfate.
Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group. Acts bactericidal and provides highly effective local treatment of primary and secondary bacterial skin infections. Active against gram-negative bacteria: Pseudomonas aeruginosa, Enterobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae; gram-positive bacteria: Staphylococcus aureus (coagulase-positive, coagulase-negative and some strains that produce penicillinase).
Indications
Dermatoses complicated by infections caused by pathogens sensitive to the drug, or with suspicion of such infections, including:
simple and allergic dermatitis;
atopic dermatitis (including diffuse neurodermatitis);
Contraindications
-lupus;
-cutaneous manifestations of syphilis;
-chickenpox;
Side effects
Local reactions: very rarely — burning sensation, erythema, exudation, pigmentation disorders, itching.
Adverse reactions that occur when using local corticosteroids (especially when using occlusive dressings): burning sensation, itching, dry skin, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, development of a secondary infection, skin atrophy, striae , prickly heat.
Adverse reactions due to tolnaftate: erythema, tingling sensation, blistering, peeling, local edema, itching, urticaria, skin irritation.