Natrilix SR 1.5 mg 30 tablets

Tradename

Natrilix SR

Natrilix SR

Compound:

Each tablet contains:

Indapamide 1.5 mg

Auxiliary components:

lactose monohydrate, hypromellose, magnesium stearate, colloidal anhydrous silicon dioxide.

Shell composition: titanium dioxide (E171), magnesium stearate, glycerol, macrogol 6000.

Properties

Antihypertensive agent (diuretic, vasodilator). In terms of pharmacological properties, it is close to thiazide diuretics (impaired reabsorption of sodium ions in the cortical segment of Henle’s loop). Increases urinary excretion of sodium, chlorine and, to a lesser extent, potassium and magnesium ions. With the ability to selectively block the «slow» calcium channels, it increases the elasticity of the arterial walls and reduces the total peripheral vascular resistance. Helps reduce left ventricular hypertrophy. Does not affect the content of lipids in blood plasma

(triglycerides, low density lipoproteins, high density lipoproteins); does not affect carbohydrate metabolism (including in pati with diabetes mellitus). Reduces the sensitivity of the vascular wall to norepinephrine and angiotensin Il, stimulates the synthesis of prostaglandin E2,

The antihypertensive effect develops by the end of the first week and lasts for 24 hours with a single dose.

Indications

-arterial hypertension.

Method of administration and dosage:

The tablets are taken orally without chewing. The daily dose of the drug is 1 tablet 1 time / day (in the morning) with a sufficient amount of liquid.

Contraindications

-lactose intolerance;

-galactosemia;

syndrome of impaired absorption of glucose / galactose;

Side effects

From the digestive system: nausea, anorexia, dry mouth, gastralgia, vomiting, diarrhea, constipation, abdominal pain, possibly the development of hepatic encephalopathy; rarely — pancreatitis.

From the side of the central nervous system: asthenia, nervousness, headache, dizziness, drowsiness, vertigo, insomnia, depression; rarely — increased fatigue, general weakness, malaise, muscle spasm, tension, irritability, anxiety.

From the respiratory system: cough, pharyngitis, sinusitis; rarely — rhinitis.