Salofalk 500 mg 20 tablets

Tradename

Salofalk

Salofalk

Composition

Each tablet contains:

Mesalazine 500 mg

Properties

Mesalazine inhibits the activity of neutrophilic lipoxygenase and the synthesis of arachidonic acid metabolites (prostaglandins and leukotrienes), which are inflammatory mediators. It inhibits migration, degranulation, phagocytosis of neutrophils, as well as the secretion of immunoglobulins by lymphocytes. Mesalazine has antioxidant properties by binding to free oxygen radicals.

Indications

Ulcerative colitis (treatment of exacerbations and maintenance therapy in remission); Crohn’s disease (mild and moderate forms in the acute phase); rheumatoid arthritis; juvenile rheumatoid arthritis.

Method of administration and dosage:

Take 1 tablet 3 times a day after meals.

Contraindications

Porphyria, anemia, severe liver dysfunction, severe renal dysfunction, deficiency of the enzyme glucose-6-phosphate dehydrogenase, children under 5 years of age, lactation period; hypersensitivity to sulfonamides and salicylic acid derivatives.

Precautions:

Use with caution in patients with impaired liver and / or kidney function, patients with bronchial asthma, allergic reactions.

Side effects

From the nervous system: headache, dizziness, tinnitus, ataxia, convulsions, sleep disturbances, hallucinations, peripheral neuropathy.

From the urinary system: renal dysfunction, interstitial nephritis.

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, anorexia, hepatitis, pancreatitis.