Sedocast 4 mg 7 chewable tablets

Tradename

Sedocast

Composition

Each chewable tablet contains:

Montelukast 4 mg

Auxiliary components:

Mannitol, microcrystalline cellulose, croscarmellose sodium, hypromellose, aspartame, strawberry flavor, magnesium stearate.

Properties

Selectively blocks leukotriene receptors. Specifically inhibits the CysLT1 receptors of cysteinyl leukotrienes (LTC4, LTD4 and LTE4) the most powerful mediators of chronic persistent inflammation that maintain bronchial hyperreactivity in bronchial asthma.

When taken orally, it is rapidly and complet absorbed: Cmax is achieved in 2-3 hours. Bioavailability is 64-73%. In the blood, it bin s to proteins by 99%. Metabolized in the liver. It is excreted mainly in the bile. Plasma Cl is 45 ml / min.

Reduces the severity of spasm of smooth muscles of bronchioles and blood vessels, edema, migration of eosinophils and macrophages; reduces mucus secretion and improves mucociliary transport. Highly active when taken orally. The bronchodilator effect develops within one day and persists for a long time.

Indications

Prevention and long-term treatment of bronchial asthma, including the prevention of symptoms of the disease in the daytime and at night, treatment of bronchial asthma in patients with hypersensitivity to acetylsalicylic acid, prevention of bronchospasm caused by exercise. Relief of symptoms of seasonal and perennial allergic rhinitis.

Method of administration and dosage:

The drug is taken orally 1 time / day, regardless of food intake. The tablet can be swallowed whole or chewed before swallowing. For th treatment of bronchial asthma, the drug should be taken in the evening. In the treatment of allergic rhinitis, the drug can be taken at any time of the day. Patients with bronchial asthma and allergic rhinitis should take 1 tablet 1 time / day in the evening.

Contraindications

— hypersensitivity to any component of the drug;

-Children under 6 years old;

-phenylketonuria.

Side effects

Side effects are usually mild and usually do not require discontinuation of the drug.

From the nervous system: headache, dizziness, drowsiness, paresthesia / gynesthesia, convulsions.

From the side of the cardiovascular system: heart palpitations.