Terbin 1% cream 15 g

Tradename

Terbin

Terbin

Composition

Each gram of cream contains 1.0% terbinafine hydrochloride

Properties

Antifungal drug for topical use with a broad spectrum of antifungal activity. Even in small concentrations, terbinafine has a fungicidal effect against dermatophytes (Trychophyton rubrum, T.mentagrophytes, T.verrucosum, T.violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), molds (mainly C. albicans) and certain dimorphic fungi (Pityrosporum orbiculare). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic.

Terbinafine specifically alters the early stage of sterol biosynthesis in fungi. This leads to a deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of the fungal cell. Terbinafine works by

inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.

Indications

prevention and treatment of fungus, fungal infections of the skin, including mycoses of the feet («fungus» of the foot), inguinal epidermophytosis (tinea cruris), fungal lesions of the smooth skin of the body (tinea corporis) caused by dermatophytes such as Trichophyton (including T. rubrum, T.

mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis and Epidermophyton floccosum;

yeast infections of the skin, mainly those caused by the genus Candida (for example, Candida albicans), in particular diaper rash;

Contraindications

— hypersensitivity to terbinafine or to any of the inactive ingredients that make up the drug.

With care: hepatic and / or renal failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive vascular disease of the extremities, children under 12 years of age (lack of sufficient clinical experience).

Precautions:

Side effects

In places where the drug is applied, redness, itching or burning sensation may appear. Allergic reactions.

Storage method:

At a temperature not higher than 25 degrees. In a dry place.