Ascosental granules 6 sachets

Tradename

Ascozental

Ascosental

Composition

Each sachet contains:

Paracetamol 500 mg

Ascorbic acid 300 mg

Auxiliary components:

Anhydrous citric acid, sucrose, orange flavor, mannitol, menthol, colodial silicone dioxide, Aerosil 200.

Properties

Combined analgesic drug.

Paracetamol has analgesic and antipyretic effects. Blocks COX-I and COX-2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX, which explains the almost complete absence of its antiinflammatory effect. The drug has no negat effect on water-salt metabolism (sodium and water retention) and the gastrointestinal

mucosa, due to the lack of effect on the synthesis of prostaglandins in peripheral tissues. The possibility of methemoglobin formation is unlikely.

Indications

as an antipyretic agent for infectious and inflammatory diseases (ARVI, including influenza);

as an anesthetic for mild and moderate pain syndrome (headache, toothache) of noninflammatory origin, for neuralgia, pain in muscles and joints, algodismenorrhea.

Method of administration and dosage:

Contraindications

-severe kidney disease;

-severe liver disease;

-renal and / or hepatic failure;

Side effects

Paracetamol: From the digestive system: rarely — nausea, very rarely — vomiting, diarrhea, pain in the epigastric region, jaundice, pancreatitis and increased activity of liver enzymes. Allergic reactions: rarely — skin rash, pruritus, urticaria, angioedema. From the hematopoietic and lymphatic system: very rarely — anemia, leukopenia.

Others: weakness.

Vitamin C. Allergic reactions: skin rash, skin flushing. Laboratory indicators: