Xithron 500 mg 5 tablets

Tradename

Xithron

Xithrone

Composition

Each tablet contains:

Azithromycin 500 mg

Auxiliary components:

Methyl cellulose, magnesium stearate, talc, croscarmellose sodium, sodium sterilized fumorate.

Properties

A broad-spectrum antibacterial drug from the group of macrolides-azalides, acts bacteriostatically. By binding to the 50S subunit of ribosomes, it inhibits peptide translocase at the translation stage, inhibits protein synthesis, slows down the growth and reproduction of bacteria, and has a bactericidal effect in high concentrations. Acts on extraand intracellular pathogens. Microorganism may be initially resistant to antibiotic action may acquire resistance to it.

Indications

@ Infectious and inflammatory diseases caused by microorganisms sensitive to the drug; e infections of the upper respiratory tract and ENT organs: pharyngitis, tonsillitis, sinusitis, otitis media; e lower respiratory tract infections: acute bronchitis, exacerbation of chronic bronchitis, pneumonia, incl. caused by atypical pathogens; infections of the skin and soft tissues:

common acne of moderate severity, erysipelas, impetigo, secondary infected dermatoses;

@ the initial stage of Lyme disease (borreliosis) erythema migrans (erythema migrans); e urinary tract infections caused by Chlamydia trachomatis (urethritis, cervicitis).

Contraindications

severe hepatic and / or renal failure;

children under 12 years of age with a body weight of less than 45 kg (for this dosage form);

-breast-feeding;

Side effects

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, loose stools, flatulence, indigestion, anorexia, constipation, discoloration of the tongue, pseudomembranous colitis, cholestatic jaundice, hepatitis, changes in laboratory parameters of liver function, liver failure, liver necrosis (possibly fatal).

Allergic reactions: itching, skin rashes, angioedema, urticaria, photosensitivity, anaphylactic reaction (in rare cases fatal), erythema multiforme, Stevens-Johnson syndrome, toxic epidermalnscrolysis.

From the side of the cardiovascular system: palpitations, arrhythmias, ventricular tachycardia, increased QT interval, bidirectional ventricular tachycardia.