Itracon 100 mg 14 capsules
Tradename
Itracon
Itracon
Composition
Each capsule contains:
Itraconazole 100 mg
Auxiliary components:
Hydroxypropyl cellulose, poloxamer, polyethylene glycol.
Properties
Triazole derivative antifungal agent. The mechanism of action is associated with the ability to inhibit cytochrome P450-dependent enzymes of sensitive fungi, which leads to disruption of the synthesis of ergosterol in the cell wall of the fungus. Has a broader spectrum of antifungal activity than ketoconazole. Active against Aspergillus spp., Blastomyces dermatitidis, Candida, Coccidioides immitis, Cryptococcus neoformans, Epidermophyton, Microsporum, Trichophyton, Histoplasma capsulatum, Malassezia furfur, Paracoccidioides brasiliensis, Spheniickii.
Indications
Vulvovaginal candidiasis, mycoses of the skin, oral cavity, eyes, onychomycosis caused by dermatophytes and / or yeasts, systemic mycoses (including systemic aspergillosis, candidiasis, cryptococcosis, histoplasmosis, sporotrichosis, paracoccidioidosis, blastomycosis and other rare systemic and tropical mycoses).
Method of administration and dosage:
The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.
Contraindications
Simultaneous ingestion of terfenadine, astemizole, mizolastine, cisapride, dofetilide, quinidine, pimozide, simvastatin, lovastatin, midazolam or triazolam; hypersensitivity to itraconazole.
Precautionary measures:
Should not be used in patients with symptoms of ventricular dysfunction and a history of congestive heart failure.
Side effects
From the side of the digestive system: abdominal pain, nausea, vomiting, constipation, increased activity of liver enzymes, cholestatic jaundice; in some cases — hepatitis.
From the side of the central nervous system and peripheral nervous system: headache, dizziness; in some cases, peripheral neuropathy.
From the side of the cardiovascular system: in some cases — edema, congestive heart failure and pulmonary edema.