
Torseretic 5 mg 30 tablets
Tradename
Torseretic
Composition
Each tablet contains:
Torasemide 5 mg
Auxiliary components: microcrystalline cellulose, lactose monohydrate, povidone, sodium carboxymethyl starch (sodium starch glycolate), magnesium stearate
Properties
«Loop» diuretic. The main mechanism of action is due to the reversible binding of torasemide to the sodium / chlorine / potassium counterporter located in the apical membrane of the thick segment of the ascending loop of Henle, as a result of this, the reabsorption of sodium ions is reduced or completely inhibited and the osmotic pressure of the intracellular fluid and water reabsorption decrease.
Torasemide, to a lesser extent than furosemide, causes hypokalemia, while it is more active and its effect is longer. The diuretic effect develops within about an hour after oral administration, reaching a maximum after 3-6 hours, and lasts from 8 to 10 hours.
Reduces systolic and diastolic blood pressu while lying and standing.
Indications
Edema syndrome of various origins, incl. with chronic heart failure, liver and kidney diseases.
Arterial hypertension.
Method of administration and dosage:
Side effects
From the side of metabolism: infrequently hypercholesterolemia, hypertriglyceridemia, polydipsia.
From the nervous system: often — dizziness, headache, drowsiness; infrequently — muscle cramps of the lower extremities; the frequency is unknown — confusion, fainting, paresthesia in the limbs.
From the side of the cardiovascular system: infrequently — extrasystole, tachycardia, increased heart rate, facial flushing; frequency unknown — excessive arterial hypotension, deep vein thrombosis, thromboembolism, hypovolemia.