Urivin granules 10 sachets

Tradename

Urivin

Composition

Each sachet contains:

Piperazine citrate 165 mg

Colchicine 0.3 mg

Kellin 1.75 mg

Atropine sulfate 0.128 mg.

Auxiliary components:

sodium bicarbonate, anhydrous citric acid, povidone, PVP, lemon oil, sucrose.

Properties

Piperazine has been known for many years as an effective drug in the treatment of gout and urinary tract lithiasis. It increases the solubility of urate in urine. The toxicity is low. Colchicine provides rapid pain relief from acute attacks of gout. The drug is specific for this condition and thus can be used as a diagnostic agent for gout and gouty arthritis. Colchicine has anti inflammatory properties. While it is very effective in treating acute gouty arthritis, it is

not effective in other types of pain. It is not an analgesic and does not affect uric acid clearance. Instead, colchicine binds to proteins in the microtubules of neutrophils. This binding, in turn, inhibits the migration of neutrophils to the inflammatory area,

Kellin has an anti-spasmodic effect on smooth muscles. Atropine sulfate is also added to relieve urinary tract spasm.

Indications

Acute and chronic gout.

Gouty arthritis.

For the prevention of urolithiasis.

Contraindications

Known hypersensitivity to any component of the drug.

Blood dyscrasia.

Acute dehydration, anuria, or hyperkalemia.

Side effects

Sometimes nausea, vomiting, abdominal pain and diarrhea may occur.

Storage method:

At a temperature not higher than 30 degrees. In a dry place.