
Netlook 40 mg 20 capsules
Tradename
Netluk
Netlook
Composition
Isotretinoin 40 mg
Auxiliary components: yellow beeswax, hydrogenated soybean oil, partially hydrogenated soybean oil, refined soybean oil;
capsule shell: gelatin, glycerol, dry substance Karion, mannitol, hydrogenated hydrolyzed starch, titanium dioxide.
Properties
Pharmacological action — anti-inflammatory, anti-seborrheic, dermatoprotective, A-vitaminlike, anti-acne.
It normalizes the terminal differentiation of cells, inhibits the proliferation of the epithelium of the ducts of the sebaceous glands, the formation of detritus, facilitates its evacuation. Reduces production and facilitates sebum production.
When taken orally, absorption is variable, bioavailability is low and variable; taking with food increases bioavailability by 2 times. Tmax
Indications
For oral administration: severe forms of acne (nodular-cystic, conglobate, acne with the risk of scarring); acne that is not amenable to other types of therapy.
Method of administration and dosage:
The optimal dosage regimen is selected by the doctor after the examination.
Contraindications
Hypersensitivity, for oral administration:
pregnancy, established or planned (teratogenic and embryotoxic effects are possible), breastfeeding period, hepatic failure, hypervitaminosis A, severe hyperlipidemia, concomitant tetracyclines therapy.
Precautions:
Side effects
From the nervous system and sensory organs: excessive fatigue, headache, increased intracranial pressure (pseudotumor of the brain: headache, nausea, vomiting, visual impairment, swelling of the optic nerve), seizures, xerophthalmia, isolated cases of visual impairment, photophobia, violation of dark adaptation (decreased acuity of twilight vision);
From the digestive tract: dryness of the oral mucosa, bleeding from the gums, inflammation of the gums, nausea, diarrhea, inflammatory bowel disease (colitis, ileitis), bleeding, pancreatitis;
From the hematopoietic system: anemia, decreased hematocrit, leukopenia, neutropenia, increase or decrease in the number of platelets, accelerated ESR.