Pepzol 40 mg 14 capsules

Tradename

Pepzol 40mg

Pepzol 40 mg

Composition

each capsule contains 40 mg of omeprazole

Auxiliary components:

Sodium lauryl sulfate, disodium hydrogen phosphate, calcium carbonate, talc, hypermylose, diethyl fvalalete, polysorb, purified water, titanium dioxide, sodium hydroxide.

Properties

Omeprazole inhibits the enzyme H + — K + _ ATPase («proton pump») in the parietal cells of the stomach and thereby blocks the final stage of the synthesis of hydrochloric acid. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus. After a single oral dose of the drug, the effect of omeprazole occurs within the first hour and lasts for 24 hours, the maximum effect is achieved after 2 hours. In patients with duodenal ulcer, taking 20 mg of omeprazole maintains an intragastric pH = 3 for 17 hours. the drug’s secretory activity is fully restored after 3-5 days.

Indications

peptic ulcer of the stomach and duodenum; reflux esophagitis; erosive and ulcerative lesions of the stomach and duodenum associated with the use of NSAlDs; stress ulcers; erosive and ulcerative lesions of the stomach and duodenum associated with Helicobacter pylori (as part of complex therapy); Zollinger-Ellison syndrome.

Mode of application:

Inside, with a small amount of water (the contents of the capsule cannot be chewed).

Contraindications

hypersensitivity to the drug; childhood; pregnancy; lactation period.

Precautions:

Before starting therapy, it is necessary to exclude the presence of a malignant process (especially with a stomach ulcer), because treatment by masking the symptomatology may delay the correct diagnosis.

Side effects

In rare cases, the following usually reversibl side effects may occur.

From the digestive system: diarrhea or constipation, nausea, vomiting, flatulence, abdominal pain, dry mouth, taste disturbances, stomatitis, transient increase in the level of liver enzymes in plasma; in patients with previous severe liver disease — hepatitis (including jaundice), liver dysfunction.

From the nervous system: headache, dizziness, agitation, drowsiness, insomnia, paresthesia, depression, hallucinations; in patients with severe concomitant somatic diseases, in patients with previous severe liver disease encephalopathy.

Storage

In a dry, dark place, at a temperature not exceeding 30C.

Packaging:

Cardboard box holds a plastic jar with 7 or 14 capsules