Doxidox 100 mg 10 capsules

Tradename

Doxidox

Composition

Each capsule contains:

Doxycycline 100 mg

Auxiliary components:

calcium stearate, lactose monohydrate, potato starch.

Properties

Semisynthetic tetracycline, broad-spectrum bacteriostatic antibiotic. Penetrating into the cell, it acts on intracellular pathogens. Suppresses the synthesis of proteins in the microbial cell, disrupts the connection of transport aminoacyl-RNA with the 30S subunit of the ribosomal membrane.

To a lesser extent than other antibiotics of the tetracycline series, it inhibits the intestinal flora, differs from them in more complete absorption and a longer duration of action. Doxycycline surpasses natural tetracyclines in the degree of antibacterial activity. In contrast to tetracycline and oxytetracycline, it has a higher therapeutic efficacy, which is manifested in treatment with 10 times lower doses, and a longer action. There is cross-resistance to other tetracyclines as well as to penicillins.

Indications

Infectious diseases caused by pathogens sensitive to doxycycline.

Method of administration and dosage:

Administered orally during or after meals.

Contraindications

hypersensitivity to doxycycline, drug components, other tetracyclines;

lactase deficiency;

-lactose intolerance;

Side effects

On the part of the digestive system: nausea, constipation or diarrhea, abdominal pain, glossitis, dysphagia, esophagitis (including erosive), gastritis, ulceration of the stomach and duodenum, pseudomembranous colitis, enterocolitis (due to the proliferation of resistant strains of staphylococcus aureus ).

Allergic reactions: maculopapular rash, pruritus, skin hyperemia, angioedema, anaphylactoid reactions, drug lupus erythematosus, erythematous rash, exfoliative dermatitis, urticaria, anaphylaxis, anaphylactic shock, anaphylactic Stevens-Jones syndrome.

From the side of the cardiovascular system: pericarditis, lowering blood pressure, tachycardia, erythema multiforme.