Zyloric 300 mg 30 tablets

Tradename

Zyloric

Zilorik

Composition

Each tablet contains:

300 mg allopurinol

Auxiliary components:

lactose monohydrate (milk sugar) — 49.00 mg; MCC — 20.00 mg; sodium carboxymethyl starch (primogel) — 20.00 mg; food gelatin — 5.00 mg; magnesium stearate — 4.00 mg; colloidal silicon dioxide (aerosil) — 2.00 mg

Properties

Allopurinol is an anti-gout drug that inhibits the synthesis of uric acid and its salts in the body. The drug has the specific ability to inhibit the xanthine oxidase enzyme involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid. As a result, the content of urates in the blood serum decreases, which prevents their deposition in tissues and kidneys.

Allopurinol in the body is converted to oxypurinol (alloxanthin), which also prevents the formation of uric acid, but is inferior in activity to allopurinol.

Indications

Treatment and prevention of gout and hyperuricemia of various origins (including in combination with nephrolithiasis, renal failure, urate nephropathy). Recurrent mixed calcium oxalate kidney stones in the presence of hyperuricosuria. Increased formation of urates due to enzyme disorders. Prevention of acute nephropathy with cytostatic and radiation therapy of tumors and leukemias, as well as with complete medical fasting.

Method of administration and dosage:

Inside, after meals, with plenty of water, 1 time per day.

Contraindications

— hypersensitivity to allopurinol or to other components of the drug;

— severe violations of liver or kidney function;

-During pregnancy and breastfeeding;

Side effects

From the side of metabolic processes:

— at the beginning of the course of treatment, an acute attack of gout may occur due to the mobilization of uric acid from gouty nodules and other depots.

From the gastrointestinal tract and liver: