Gaptin 400 mg 30 capsules

Tradename

Gaptin 400 mg

Composition

Each capsule contains:

Gabapentin 400mg

Properties

Gabapentin is a new generation antiepileptic drug that increases levels of gamma-aminobutyric acid (GABA). Reduces the flow of calcium ions, which plays an important role in the onset of neuropathic pain. Other mechanisms of action of Gabapentin in neuropathic pain are the reduction of glutamate-dependent neuronal death.

Indications

treatment of neuropathic pain in diabetic polyneuropathy, postherpetic neuralgia, neuropathic low back pain and trigeminal neuralgia. In the treatment of partial seizures with or without secondary generalization. As an adjuvant in patients who do not respond or are intolerant of standard anti-epileptics.

Mode of application:

on the first day, 100 mg 3 times a day, then 200 mg 3 times a day (second day), then 300 mg 3 times a day (third day). The dose is increased on the 4th day to 400 mg 3 times a day and gradually increased to 2,400 mg per day by the third week. The safe daily dose of Gabapentin is 3600 mg, given that the total daily dose should be divided into 3 single doses in each case. The first dose should be given at bedtime to avoid any side effect. In patients with impaired renal failure or those undergoing hemodialysis, dose adjustment is necessary according to the doctor’s instructions. Care must be taken when discontinuing the drug with gradual withdrawal by reducing the dose within 7 days. Children 6 years and older: The starting dose should be 10 to 15 mg / kg / day, and the effective dose is achieved within no more than 3 days. The effective dose in children 6 years of age and older is 25 to 35 mg / kg / day. Dosages up to 50 mg / kg / day were well tolerated. The total daily dose should be divided into 3 single doses, the maximum interval should not exceed 12 hours.

Contraindications

with hypersensitivity to any of the ingredients; pregnancy and lactation.

Precautionary measures:

patients are not advised to drive or operate any equipment during Gaptin therapy. use with caution in patients with mixed seizure syndrome. Patients receiving gabapentin should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and / or any unusual changes in mood or behavior.

Side effects

the most common are drowsiness, back pain, dizziness, fatigue, headache, nausea and vomiting.

Storage method:

Store at a temperature of 30C in a dry place out of the reach of children.