Depakine 200 mg 40 tablets

Tradename

Depakine 200 mg

Depakine 200 mg

Composition

Each tablet contains:

200mg sodium valproate.

Auxiliary components:

silicon dioxide, hypromellose, ethylcellulose, sodium saccharinate, colloidal silicon dioxide, Opadray II white, polyvinyl alcohol, macrogol, talc, titanium dioxide.

Properties

Antiepileptic drug. It is believed that the mechanism of action is associated with an increase in the content of GABA in the central nervous system, which is due to inhibition of GABA transaminase, as well as a decrease in the reuptake of GABA in brain tissues. This, apparently, leads to a decrease in the excitability and convulsive readiness of the motor zones of the brain. It helps to improve the mental state and mood of patients.

Indications

Epileptic seizures: generalized, focal (focal, partial) with simple and complex symptoms, small. Convulsive syndrome in organic brain diseases.

Method of administration and dosage:

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Contraindications

Severe liver dysfunction; severe dysfunction of the pancreas; porphyria; hemorrhagic diathesis; severe thrombocytopenia; I trimester of pregnancy; lactation (breastfeeding); hypersensitivity to valproic acid.

Precautionary measures:

It is used with caution in patients with pathological changes in the blood, with organic brain diseases, a history of liver disease, hypoproteinemia, and impaired renal function.

Side effects

From the side of the central nervous system: trembling of the hands or arms is possible; rarely — changes in behavior, mood or mental state, diplopia, nystagmus, spots before the eyes, impaired coordination of movements, dizziness, drowsiness, headache, unusual agitation, restlessness or irritability.

On the part of the digestive system: mild cramps in the abdomen or in the stomach, loss of appetite, diarrhea, indigestion, nausea, vomiting are possible; rarely — constipation, pancreatitis.

On the part of the blood coagulation system: thrombocytopenia, prolonged bleeding time.