Diamicron 80 mg 20 tablets

Trade name:

Diamicron 80 mg

Compound:

Properties

Gliclazide reduces platelet adhesion and aggregation, slows down the development of a parietal thrombus, and increases vascular fibrinolytic activity. Normalizes vascular permeability. It has anti-atherogenic properties: it lowers the concentration of total cholesterol (Xc) and Xc-LDL in the blood, increases the concentration of Xc-HDL, and also reduces the amount of free radicals. Prevents the development of microthrombosis and atherosclerosis. Improves microcirculation. Reduces the sensitivity of blood vessels to adrenaline.

In diabetic nephropathy against the background of long-term use of gliclazide, there is a significant decrease in proteinuria.

Indications

Dosage and administration

The recommended daily dose is 2 tablets per day, the frequency of administration is 2 times / day before meals. It is recommended to take at the same time. Dosing individually depending on fasting and 2 hours after a meal, as well as on the clinical manifestations of the disease.

Contraindications

Precautionary measures:

With the development of hypoglycemia, if the patient is conscious, glucose (or a sugar solution) is administered orally. In the event of loss of consciousness, glucose is administered intravenously or glucagon s.c., i.m. or i.v. After the restoration of consciousness, it is necessary to give the patient food rich in carbohydrates in order to avoid the recurrence of hypoglycemia.

With the simultaneous use of gliclazide with verapamil, regular monitoring of blood glucose levels is necessary; with acarbose — careful monitoring and correction of the dosing regimen of hypoglycemic agents is required.

Side effects

From the hemopoietic system: in some cases — thrombocytopenia, agranulocytosis or leukopenia, anemia (usually reversible).

From the endocrine system: in case of overdose — hypoglycemia.

Allergic reactions: skin rash, itching.