
Nevanac 1mg/ml drops 5 ml
Tradename
Nevanac
Nevanak
Compound:
Each 1 ml suspension contains:
Nepafenac 1 mg
Auxiliary components:
benzalkonium chloride (in the form of a 50% solution), carbomer (974R), tyloxapol, disodium edetate, mannitol, sodium chloride, sodium hydroxide and / or hydrochloric acid — to adjust the pH, purified water.
Properties
Nepafenac is a non-steroidal anti-inflammatory drug with analgesic action. When applied topically, nepafenac penetrates the cornea of the eye and, under the influence of the hydrolase enzyme, is converted into the active form — amfenac. Amfenac inhibits the action of cyclooxygenase (prostaglandin — H synthase), an enzyme necessary for the production of prostaglandins.
Clinical Efficiency
In clinical studies on the effectiveness of Nepafenac suspension in the prevention and treatment of postoperative pain and inflammation in patients after cataract surgery, and to reduce the risk of postoperative macular edema in patients with diabetes who underwent cataract surgery, its high efficacy was established.
Indications
— prevention and treatment of postoperative pain and inflammation after cataract surgery
— reduced risk of postoperative macular edema associated with cataract surgery in diabetic patients.
Dosage and administration
Only for local use in ophthalmology.
Shake the bottle before use.
When using more than one topical ophthalmic drug, the interval between the use of drugs should be at least 5 minutes.
Contraindications
Individual hypersensitivity to the active substance, any excipient or other non-steroidal anti-inflammatory drugs (NSAIDs).
Precautionary measures:
The use of NSAIDs locally can lead to the development of keratitis. In some susceptible patients, prolonged topical use of NSAIDs can lead to epithelial damage, corneal thinning, corneal erosion, corneal ulceration or perforation. Such phenomena can threaten vision. Patients who develop signs of corneal damage should immediately stop using Nevanak, and the condition of the cornea should be carefully monitored.
Side effects
Uncommon: keratitis, punctate keratitis, corneal epithelial defect, allergic conjunctivitis, eye pain, foreign body sensation, eyelid margin peeling
Rare: Blurred vision, photophobia, dry eyes, blepharitis, eye irritation, itchy eyes, discharge from the eyes, increased tearing.
Ophthalmic disorders: