Tobrin 0.3% drops 5 ml
Tradename
Tobrin
Tobrin
Compound:
Each ml contains:
Tobramycin 3 mg
Auxiliary components:
benzalkonium chloride, disodium edetate dihydrate, sodium chloride, hypromellose, water for injections.
Properties
Broad-spectrum aminoglycoside antibiotic. It has a bactericidal effect, disrupting protein synthesis and the permeability of the cytoplasmic membrane of bacteria.
Highly active against Pseudomonas aeruginosa.
Tobramycin is active against gram-negative bacteria: Escherichia coli, Proteus spp. (indole-positive and indole-negative strains), Klebsiella spp., Serratia spp., Providencia spp., Enterobacter spp., Shigella spp., Salmonella spp., Citrobacter spp., Haemophilus influenzae; Gram-positive bacteria: Staphylococcus spp. (including strains producing penicillinase).
Indications
For topical use: eye infections (as part of combination therapy). And severe infectious and inflammatory diseases caused by pathogens sensitive to tobramycin.
Dosage and administration
The optimal dosing regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
Individual, depending on the indications, the severity of the course of the disease, the age of the patient.
The average adult dose is 1-2 drops in each eye every 4 hours.
Contraindications
Hypersensitivity to tobramycin and other aminoglycosides.
Precautionary measures:
Systemic use of tobramycin is possible when the expected benefit of treatment outweighs the risk of side effects in the following cases: in patients with impaired renal function, hearing, myasthenia gravis and parkinsonism.
Side effects
From the side of the central nervous system and peripheral nervous system: ototoxic effect, headache, lethargy, disorientation, impaired neuromuscular transmission.
From the digestive system: nausea, vomiting, increased levels of hepatic transaminases and bilirubin in the blood.
From the hemopoietic system: anemia, granulocytopenia, thrombocytopenia.