Flagyl 500 mg 20 tablets

Trade name:

flagyl

Flagil

Properties

Synthetic antibacterial and antiprotozoal drug of the 5-nitroimidazole group. The drug has an antibacterial, antiprotozoal effect. The mechanism of action is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microorganism cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.

Indications

Infections caused by anaerobic pathogens: wound infection, infection of the respiratory system, urinary tract, intestines; prevention of anaerobic infection before intestinal surgery; trichomoniasis, amoebiasis, giardiasis, Crohn’s disease.

Dosage and administration

Inside, during or after a meal, without chewing.

The course of treatment is determined by the doctor after the tests: On average, the course of treatment: Children 2-5 years old — 250 mg / day; 5-10 years — 250-375 mg / day, children 10-15 years old — 500 mg / day and adults — 500 mg 2-3 times a day. The course of treatment is 5-10 days.

With severe renal impairment (CC less than 10 ml / min), the daily dose should be halved.

Contraindications

— leukopenia (including history);

-organic lesions of the central nervous system (including epilepsy);

— liver failure (in case of high doses);

Side effects

From the digestive system: diarrhea, anorexia, nausea, vomiting, intestinal colic, constipation, metallic taste in the mouth, dry mouth, glossitis, stomatitis, pancreatitis.

From the nervous system: dizziness, incoordination, ataxia, confusion, irritability, depression, irritability, weakness, insomnia, headache, convulsions, hallucinations, peripheral neuropathy.

Allergic reactions: urticaria, skin rash, skin flushing, nasal congestion, fever, arthralgia.