Lamisil cream 1% 15 g

Tradename

Lamisil

Lamisil

Compound:

Each gram of cream contains:

Terbinafine hydrochloride 10 mg

Auxiliary components:

benzyl alcohol, polysorbate 60 (tween 60), sorbitan monostearate, cetyl alcohol, isopropyl myristate, cetyl palmitate, sodium hydroxide, purified water.

Properties

An antifungal drug for topical use with a wide spectrum of antifungal activity. Even at low concentrations, terbinafine has a fungicidal effect against dermatophytes (Trychophyton rubrum, T.mentagrophytes, T.verrucosum, T.violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), molds (mainly C.albicans) and certain dimorphic fungi (Pityrosporum orbiculare). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic.

Terbinafine specifically alters the early stage of sterol biosynthesis occurring in fungi. This leads to a deficiency of ergosterol and intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus.

Indications

— prevention and treatment of fungus, fungal infections of the skin, including mycoses of the feet («fungus» of the foot), inguinal epidermophytosis (tinea cruris), fungal infections of the smooth skin of the body (tinea corporis) caused by dermatophytes such as Trichophyton (including T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis and Epidermophyton floccosum;

— yeast infections of the skin, mainly those caused by the genus Candida (for example, Candida albicans), in particular diaper rash;

— versicolor versicolor (Pityriasis versicolor) caused by Pityrosporum orbiculare (also known as Malassezia furfur).

Dosage and administration

Outwardly.

Adults and children from 12 years of age:

Before applying the cream, clean and dry the affected areas. The cream is applied once or twice a day with a thin layer on the affected skin and adjacent areas and lightly rubbed. For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the places where the cream is applied can be covered with gauze, especially at night. The average duration of treatment: ringworm of the trunk, legs — 1 week 1 time per day; tinea pedis — 1 week 1 time per day; skin candidiasis — 1-2 weeks 1 or 2 times a day; versicolor versicolor: 2 weeks 1 or 2 times a day.

Contraindications

— hypersensitivity to terbinafine or to any of the inactive ingredients that make up the drug.

With caution: liver and / or kidney failure, alcoholism, inhibition of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive diseases of the vessels of the extremities, children under 12 years of age (lack of sufficient clinical experience).

Precautionary measures:

Side effects

Redness, itching or burning sensation may appear in the places of application of the drug. Allergic reactions.

Storage method:

Store at a temperature not exceeding 30 degrees.