Panadol Extra 24 tablets

Tradename

Panadol Extra

Panadol Extra

Compound:

Each tablet contains:

Paracetamol 500 mg

Caffeine 65 mg

Auxiliary components:

Starch, potassium sorbitol, talc, stearic acid, croscarmellose sodium.

Properties

The drug has an analgesic and antipyretic effect. Panadol Extra contains a combination of the two active ingredients paracetamol and caffeine. Paracetamol blocks cyclooxygenase (COX) in the central nervous system, affecting the centers of pain and thermoregulation (in inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX), which explains the almost complete absence of an anti-inflammatory effect. The lack of influence on the synthesis of Pg in peripheral tissues determines the absence of a negative effect on the water-salt metabolism (sodium and water retention) and the gastrointestinal mucosa. Caffeine stimulates the psychomotor centers of the brain, has an analgesic effect, enhances the effects of analgesics, eliminates drowsiness and fatigue, and increases physical and mental performance.

Indications

-headache;

-migraine;

-toothache;

Contraindications

— hypersensitivity to the components of the drug, severe violations of the liver or kidneys

-absence of glucose-6-phosphate dehydrogenase

-blood diseases

Side effects

At recommended doses, the drug is usually well tolerated. Paracetamol rarely causes side effects. An allergic reaction may occur in the form of skin rashes, itching, Quincke’s edema. Rarely — leukopenia, thrombocytopenia, methemoglobinemia, agranulocytosis, as well as sleep disturbance, tachycardia. With prolonged use in high doses, the likelihood of hepatotoxic and nephrotoxic effects increases and blood picture control is necessary.

Storage

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains 2 blisters of 12 tablets, paper instructions.