Downoprazol 20/1100 mg 14 capsules

Tradename

Downoprazol

Compound:

Each capsule contains:

Omeprazole 20 mg

Sodium bicarbonate 1100 mg

Properties

Omeprazole inhibits the enzyme H7K + -ATPase, which is responsible for the secretion of hydrochloric acid by the acidic cells of the stomach. Due to this selective intracellular action, independent of membrane receptors, omeprazole belongs to an independent class of hydrochloric acid secretion inhibitors that block the final phase of the secretory process. Due to its mechanism of action, omeprazole reduces not only basal acid secretion, but also that secretion that can be stimulated, regardless of the type of stimulant; it raises the pH value and reduces the secretory volume of hydrochloric acid in the stomach.

Sodium bicarbonate:

When taken orally, it quickly neutralizes the hydrochloric acid of gastric juice and has a quick, but short-term antacid effect. Irritates the receptors of the gastric mucosa, enhances the release of gastrin with secondary activation of secretion, can cause discomfort in the stomach (due to its stretching) and belching.

Indications

• Peptic ulcer of the stomach and duodenum (including prevention of recurrence),

• Reflux esophagitis,

• Hypersecretory conditions (Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract, polyendocrine adenomatosis, systemic mastocytosis).

Dosage and administration

Adults over 18:

Take 1 capsule per day. The course of treatment is selected by the doctor.

On average, the course of treatment is 4-8 weeks.

Contraindications

childhood;

pregnancy;

lactation period;

Side effects

From the digestive system: diarrhea or constipation, abdominal pain, nausea, vomiting, flatulence.

From the nervous system: in patients with severe concomitant somatic diseases — headache, dizziness, agitation, depression, in patients with previous severe liver disease — encephalopathy.

From the musculoskeletal system: in some cases — arthralgia, myasthenia gravis, myalgia.

Storage

Store at a temperature not exceeding 30 degrees.

Package:

The cardboard box contains a blister of 14 capsules, paper instructions.