Coversyl Plus 10/2.5mg 15 tablets

Tradename

Coversil plus

Coversyl Plus

Compound:

Each tablet contains:

Perindopril arginine 10 mg

Indapamide 2.5 mg

Auxiliary components:

Lactose monohydrate, magnesium stearate, maltodextrin, sodium glycodal, glycerol, hypromellose, macrogol, titanium dioxide.

Properties

The combination of perindopril and indapamide enhances the antihypertensive effect of each of them.

Indapamide:

Indapamide belongs to the group of sulfonamides, in terms of pharmacological properties it is close to thiazide diuretics. Indapamide inhibits the reabsorption of sodium ions in the cortical segment of the loop of Henle, which leads to an increase in the excretion of sodium ions, chloride ions and, to a lesser extent, potassium and magnesium ions, thereby increasing diuresis and reducing blood pressure.

Indications

-essential hypertension;

— in patients with arterial hypertension and type 2 diabetes mellitus to reduce the risk of developing microvascular complications (from the kidneys) and macrovascular complications from cardiovascular diseases.

Dosage and administration

Oral intake.

The drug is taken 1 tablet per day, preferably in the morning before meals.

For elderly patients, the drug is prescribed under the condition of normal kidney function, while the degree of reduction in blood pressure should be monitored.

Contraindications

— hypersensitivity to indapamide and other sulfonamides;

— severe renal dysfunction (CC less than 30 ml / min);

— hepatic encephalopathy;

Side effects

The most common side effects were:

— for perindopril: dizziness, headache, paresthesia, dysgeusia, blurred vision, vertigo, tinnitus, hypotension, cough, shortness of breath, abdominal pain, constipation, dyspepsia, diarrhea, nausea, vomiting, pruritus, skin rash, muscle spasms and asthenia;

— for indapamide: hypersensitivity reactions, mainly skin, in patients predisposed to allergic and asthmatic reactions, and maculo-papular rash.