
Micardis 80 mg 28 tablets
Tradename
Micardis
Micardis
Compound:
Each tablet contains:
Telmisartan 80 mg
Auxiliary components:
sodium hydroxide, polyvidone (kollidon 25), meglumine, sorbitol, magnesium stearate.
Properties
Antihypertensive agent, angiotensin II receptor antagonist (type AT1). It has a very high affinity for this receptor subtype. Selectively and for a long time binding to receptors, telmisartan displaces angiotensin II from its association with AT1 receptors. Does not show affinity for other subtypes of AT receptors. The functional significance of other subtypes of receptors and the effect of elevated (as a result of the appointment of telmisartan) levels of angiotensin II on them is not known. Telmisartan reduces plasma aldosterone levels, does not inhibit plasma renin, does not block ion channels, does not inhibit ACE (kinase II), which also destroys bradykinin. Therefore, there are no side effects associated with bradykinin.
Indications
-arterial hypertension;
— reduction of cardiovascular morbidity and mortality in patients aged 55 years and older with a high risk of cardiovascular disease.
Mode of application:
Contraindications
Biliary tract obstruction, severe liver and kidney dysfunction, pregnancy, lactation (breastfeeding), hypersensitivity to telmisartan.
Precautionary measures:
With caution, telmisartan is used for violations of liver function, peptic ulcer of the stomach and duodenum in the acute stage, other diseases of the gastrointestinal tract, stenosis of the aorta and mitral valve, obstructive hypertrophic cardiomyopathy, coronary artery disease, heart failure.
Side effects
From the side of the central nervous system: headache, dizziness, fatigue, insomnia, anxiety, depression, convulsions.
From the digestive system: abdominal pain, dyspepsia, nausea, diarrhea, increased activity of hepatic transaminases.
From the respiratory system: cough, pharyngitis, infections of the upper respiratory tract.
Storage
Store at a temperature not exceeding 30 degrees.
Package:
The cardboard box contains 2 blisters of 14 tablets, paper instructions.