Epilate 10 mg capsules

tradename

Epilate

Shaved

composition

Each softgel contains:

Nifedipine 10mg

Auxiliary components:

Glycerin, polyethylene glycol 400, sodium saccharin, peppermint oil, polysorbitol 80, purified water.

properties

Selective calcium channel blocker class II, dihydropyridine derivative. It inhibits the entry of calcium into cardiomyocytes and vascular smooth muscle cells. It has antianginal and hypotensive effects. Reduces the tone of vascular smooth muscle. It dilates the coronary and peripheral arteries, reduces peripheral vascular resistance, blood pressure and slightly — myocardial contractility, reduces afterload and myocardial oxygen demand. Improve coronary blood flow. Virtually no antiarrhythmic activity. Does not inhibit myocardial conduction.

indications

Prevention of angina attacks (including vasospastic angina), in some cases — relief of angina attacks; arterial hypertension, hypertensive crises; Raynaud’s disease.

Dosage and Administration

individual. For oral administration, the initial dose is 10 mg 3-4 times / day. If necessary, the dose is gradually increased to 20 mg 3-4 times / day. In special cases (variant angina pectoris, severe arterial hypertension) for a short time, the dose can be increased to 30 mg 3-4 times / day. For the relief of a hypertensive crisis, as well as an attack of angina pectoris, 10-20 mg (rarely 30 mg) can be used sublingually.

Contraindications

Arterial hypotension (systolic blood pressure below 90 mm Hg), collapse, cardiogenic shock, severe heart failure, severe aortic stenosis; hypersensitivity to nifedipine.

Precautionary measures:

Nifedipine should only be used in a clinical setting under the strict supervision of a physician in acute myocardial infarction, severe cerebrovascular accident, diabetes mellitus, impaired liver and kidney function, in malignant arterial hypertension and hypovolemia, as well as in patients on hemodialysis.

side effects

From the side of the cardiovascular system: hyperemia of the skin, a feeling of warmth, tachycardia, arterial hypotension, peripheral edema;

From the digestive system: nausea, heartburn, diarrhea;

From the side of the central nervous system and peripheral nervous system: headache;