
Albendazole 200mg/5ml suspension 30ml
Tradename
Albendazole
Albendazole
Compound:
Each 10 ml suspension contains:
Albendazole 400 mg
Auxiliary components:
Sucrose, microcrystalline cellulose, croscarmellose sodium, methylcellulose, methyl parahydroxybenzoate, sodium lauryl sulfate, propyl parahydroxybenzoate, citric acid monohydrate, banana flavor, purified water.
Properties
Albendazole is a benzimidazole derivative with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. Albendazole exerts larvicidal, ovocidal, and anthelmintic effects, presumably by inhibiting tubulin polymerization. This causes metabolic disturbances in helminths, including energy depletion (suppression of glucose uptake), which leads to immobilization and then destruction of susceptible helminths.
Indications
Echinococcosis, neurocysticercosis, nematodes (ascariasis, trichuriasis, ankylostomiasis, enterobiasis, strongyloidiasis), trematodes (opisthorchiasis), giardiasis, microsporidiosis, mixed helminthiases. As an aid in the surgical treatment of echinococcosis cysts.
Dosage and administration
When taken orally, a single dose is 400 mg. The frequency and duration of use depend on the indications and treatment regimen.
Contraindications
Pathologies of the retina, pregnancy, lactation (breastfeeding), children under 1 year of age (for all dosage forms), hypersensitivity to albendazole.
Precautionary measures:
Albendazole is used with caution in patients with inhibition of bone marrow hematopoiesis, liver failure, cirrhosis of the liver, pathology of the retina.
Side effects
From the digestive system: abdominal pain, nausea, vomiting, increased activity of hepatic transaminases.
From the side of the central nervous system: headache, dizziness, meningeal symptoms.
From the hemopoietic system: leukopenia, granulocytopenia, agranulocytosis, thrombocytopenia, pancytopenia.