Dexatrol ear/eye drops 5 ml

Tradename

Dexatrol

Dexatrol

Compound:

Each 1 ml of the drug contains:

Dexamethasone 1 mg

Polymyxin B 6000 IU

Neomycin 3.5 mg

Auxiliary components:

Hydroxypropyl methylcellulose, sodium benzalkonium, disodium edetate, sodium chloride, polysorbitol, sodium hydroxide, water for injection.

Properties

Combined preparation for topical use in ophthalmology.

Neomycin has a bactericidal effect, disrupting the bacterial cell protein synthesis. Active against Staphylococcus aureus, Corynebacterium diphteriae, Streptococcus viridans, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes and Haemophilus influenzae.

The mechanism of action of polymyxin B is mainly due to the blockade of the permeability of the cytoplasmic membrane of bacterial cells. Active against Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae and Koch-Weeks bacillus.

Indications

Inflammatory conditions of the eye and ear accompanied by superficial bacterial infection or risk of bacterial infection, treatable with corticosteroids, such as:

— inflammation of the conjunctiva of the eyelid or eyeball;

— inflammation of the cornea and anterior segment of the eye;

Dosage and administration

Eye drops: Apply externally 1-2 drops in each eye, can be applied up to 6 times a day.

Ear drops:

Apply 4 drops 3-4 times a day.

Contraindications

Infectious or traumatic damage to the eardrum; hypersensitivity to the components of the combination.

Precautionary measures:

Do not exceed recommended doses. Be wary appoint glaucoma, cataracts.

Side effects

Local: Allergic reactions, accompanied by itching and swelling of the eyelids, conjunctival hyperemia. Side effects due to the steroid component: increased intraocular pressure with possible subsequent development of glaucoma, damage to the optic nerve and visual fields (when using the drug for more than 10 days, monitoring of intraocular pressure is necessary); posterior subcapsular cataract, slowing down the wound healing process. Topical application of steroids for diseases that cause thinning of the cornea or sclera can lead to their perforation.

Secondary infection: The development of a secondary infection is observed after the use of combined preparations containing corticosteroids in combination with antibiotics.

Storage method: